Although conventional metal IVC filters can reduce the incidence of PE to 1-2%, many are fraught with mounting complications as they remain in the body for prolonged duration. Most IVC filters are placed with the intention to be retrieved within weeks as recommended by the FDA. However, only a small percentage of patients (4-7% in statewide studies) return for the subsequent retrieval procedure. Complications that increase with indwell duration include device fracture and embolization, IVC thrombosis, IVC perforation and impaling of neighboring organs (aorta, kidney, stomach, spine, etc.).
In contrast, the absorbable filter is made of polydioxanone, a flexible absorbable polymer that has been FDA approved for surgical applications for 40 years. Adient Medical, working with its collaborative partner University of Texas MD Anderson Cancer Center, has demonstrated that polydioxanone residing in the central venous system maintains sufficient strength throughout the indicated protection period to prevent pulmonary embolism and then vanishes in about 6 months, well beyond the life of an acute clot that resorbs in the filter within about 3 weeks. The flexible polymer is incapable of perforating the IVC and impaling neighboring organs.